CHEMOTHERAPY has become an accepted method of cancer treatment in small animal practice and the indications for cytotoxic drugs are ever increasing. Yet, none of the products available are licensed for veterinary application and, to many veterinary surgeons, the use of cytotoxic drugs remains an unfamiliar and complex subject. In this, the first of two articles addressing options for the use of chemotherapy in small animal practice, the basic principles of anticancer treatment are discussed, with consideration of toxicity and safety issues. Specific indications for cytotoxic drugs, treatment protocols and the results that can be achieved with the use of such agents in small animal patients will be discussed in the next issue.
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