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Farm Animal Practice
Bovine virus diarrhoea virus - strategic decisions for diagnosis and control
  1. Joe Brownlie

    Joe Brownlie is head of the department of veterinary pathology at the Royal Veterinary College. He is engaged in research of viral pathogenesis in cattle and was responsible, with his coauthors, for the first definition of the aetiology of fatal mucosal disease and the development of an inactivated BVDV vaccine.

    ,
  2. Ian Thompson

    Ian Thompson is Senior Vericore Fellow at the RVC, heading the immunology section for the development of novel veterinary vaccines.

    and
  3. Andrew Curwen

    Andrew Curwen, previously Veterinary Services Manager with Vericore, has recently joined Bayer, within the technical services department of its Animal Health Group. He is a council member of the BCVA.

Abstract

IN the 15 years since the last In Practice article on bovine virus diarrhoea virus (BVDV) (Brownlie 1985), there has been an explosion in the understanding of the molecular mechanisms of viral replication and mutation, especially those related to biotypic variation. Hand in hand has come a greater understanding of the importance of BVDV as a primary pathogen of cattle, particularly as a cause of reproductive loss. A BVDV vaccine is now available in the UK, giving better prospects for protection against infection. However, for the veterinary clinician, the strategic decisions regarding diagnosis, control and vaccination continue to pose difficult dilemmas and it is on these issues that this article focuses.

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