Article Text

Companion Animal Practice
Bleeding disorders in dogs
  1. Ian Johnstone

    Ian Johnstone is associate professor in the department of biomedical sciences at Ontario Veterinary College, University of Guelph. His interest in bleeding disorders began early in his veterinary career and led to an MSc and a PhD for studies on cardiovascular pathophysiology and basset hound thrombopathia, respectively. Since joining the Ontario Veterinary College in 1978, he has taught extensively in clinical and paraclinical areas of the veterinary programme. His research interests have focused on comparative studies on the haemostatic mechanism in domestic animals, and the detection and characterisation of inherited and acquired abnormalities in different animal species.

2. Acquired disorders


THIS article reviews the pathogenesis, clinical and laboratory diagnosis, and treatment of the major acquired haemostatic disorders that have been described in the dog. As with inherited haemostatic disorders (see Part 1, In Practice, January 2002, pp 2-10), the clinical expression of the bleeding associated with acquired disorders can sometimes be helpful in differentiating between primary (platelet or vascular) and secondary (coagulation) defects. However, unlike their inherited counterparts, acquired bleeding disorders usually result from multiple defects in the haemostatic response; since both primary and secondary defects may occur concurrently, the nature of the bleeding can vary considerably, and may show characteristics of both coagulation and platelet deficiencies. Appropriate haemostatic screening tests can provide valuable assistance in the detection and differentiation of these disorders.

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