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Companion Animal Practice
Clinical approach to feline eosinophilic granuloma complex
  1. Aiden Foster

    Aiden Foster graduated in 1982 with a degree in biology from Nottingham University, where he developed an interest in immunology and parasitology. He qualified as a veterinary surgeon from Bristol in 1987 and worked in mixed practice and with the PDSA before completing a PhD on allergic skin disease in the cat. He undertook a residency in veterinary dermatology at the School of Veterinary Medicine, Madison, Wisconsin, USA, and then returned to Bristol where he works for the dermatology service. He is a diplomate of the American College of Veterinary Dermatology


CATS frequently present with various manifestations of the so-called eosinophilic granuloma complex (EGC). Many cases are considered to have an underlying allergic aetiology, especially those with recurrent and multiple lesions. Allergic causes include fleas and other insects and, occasionally, environmental and dietary antigens may be implicated. Initial investigations may include skin cytology, scrapes for ectoparasites and skin biopsy; in chronic cases, the clinician has to evaluate possible allergen exposure and, particularly, the effectiveness of flea control measures. Numerous types of medication have been recommended for chronic cases, but compliance with oral products is often poor and this syndrome of eosinophilic skin disease remains a therapeutic challenge for both owners and their veterinary surgeons. This article describes the key diagnostic features of EGC and discusses the options available for therapy.

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