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Companion Animal Practice
Diagnosis and management of chronic kidney disease in dogs and cats
  1. Yvonne McGrotty

    Yvonne McGrotty graduated from Glasgow in 1997 and worked in small animal practice for two years before returning to Glasgow to specialise in internal medicine. She currently runs a private referral clinic, based at Broadleys Veterinary Hospital in Stirling. She also works as a clinical pathologist for Axiom Veterinary Laboratories. She is a diplomate of the European College of Veterinary Internal Medicine and is a recognised European veterinary specialist in internal medicine.

Abstract

CHRONIC kidney disease is a commonly encountered problem in small animal practice and is typically progressive, resulting in significant morbidity and mortality in both cats and dogs. Initial renal damage can result from a large number of infectious, immune‐mediated, congenital, metabolic, neoplastic, traumatic and obstructive disease processes, and some forms (eg, urinary tract obstruction) can be reversed if treated promptly. Common causes of renal damage include renal ischaemia or exposure to nephrotoxins (eg, aminoglycosides, ethylene glycol). As chronic renal disease progresses, more and more nephrons become non-functional and clinical signs of renal failure become apparent. This article highlights the key markers of renal function, discusses the common consequences of chronic kidney disease and outlines some renoprotective therapies.

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