Mast cell tumours (MCTs) are among the most common cutaneous tumours seen in cats and most can be managed in practice. The aetiology is unknown, although a genetic predisposition has been proposed in some breeds. MCTs usually present as a solitary mass. The most common site for cutaneous tumours is on the head, although the trunk and limbs may also be affected. The spleen is the most common site for visceral MCTs. This article describes the approach to take when presented with a cat with a MCT, the histological and immunohistological prognostic indicators, and the different treatments available.
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