The increasing use of balanced anaesthetic protocols, as well as more animals that are receiving long-term medication being presented for anaesthesia, means the potential for drug interactions during anaesthesia is high. It is important to know about the possible deleterious interactions that may occur, both in vitro and in vivo, to ensure optimal patient safety, as well as about the possible beneficial effects that may result from synergistic drug behaviour. This article explains the classification of drug interactions and discusses some common interactions – both positive and negative – that clinicians may face when administering anaesthetic agents to dogs and cats.
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