Table 1

Drugs used in the treatment of intestinal disease in rabbits

Dose and route of administrationComments
Antibiotics
 Enrofloxacin20 mg/kg every 24 hours, po or scAdministration via the sc route can cause tissue damage. Licensed for rabbits
 Marbofloxacin4 mg/kg every 24 hours, po, sc or iv
 Metronidazole20 mg/kg every 12 hours, po
 Trimethoprim-sulfadiazine30 mg/kg every 12 hours, scCan also be used to treat coccidiosis
 Trimethoprim-sulfamethoxazole*30 mg/kg every 12 hours, poCan also be used to treat coccidiosis (10-day course)
Antiparasitics
 Amprolium20 mg/kg every 24 hours, poUsed to treat coccidiosis (5-day course)
 Fenbendazole10 to 20 mg/kg every 24 hours, poUsed to treat Passalurus ambiguus, for which the dose should be repeated after 14 days
 Ivermectin0·2 to 0·4 mg/kg, po or scNot effective for P ambiguus. A single dose can be used for other roundworms
 Piperazine200 mg/kg, poRepeat after 2 to 3 weeks
 Praziquantel5 to 10 mg/kg, po, sc or imUsed to treat cestode infections, for which the dose should be repeated after 10 days
 Selamectin6 mg/kg, topicallyUsed to treat roundworm infections
 Sulfadimethoxine50 mg/kg once, po, then 25 mg/kg every 24 hours, poUsed to treat coccidiosis (10- to 20-day course)
Miscellaneous
 Cholestyramine*500 mg/kg every 12 hours, poUsed to treat enterotoxaemia. Binds to bacterial toxins
 Loperamide hydrochloride*0·1 mg/kg every 8 hours for 3 days, then every 24 hours for 2 days, poCan be useful in cases of dysbiosis
  • im Intramuscularly, iv Intravenously, po orally, sc subcutaneously

  • * Not licensed for use in animals, so the prescribing cascade must be followed

  • For details of prokinetics, analgesics and fluid therapy, see Table 2 in Part 1